From the Journals

What's Heart Disease Got to Do With It?

Large meta-analysis explores how depression, anxiety, PTSD, and sleep disorders affect heart health

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A systematic review in JAMA Psychiatry reveals that mental health conditions, notably depression, anxiety, PTSD, and sleep disorders, significantly elevate the risk of acute coronary syndrome (ACS) events. Analyzing data from 25 studies with over 22 million participants, researchers found PTSD linked to a 2.73 times greater risk of acute myocardial infarction (AMI). The study suggests integrating mental health management into cardiovascular care could enhance patient outcomes but acknowledges limitations due to study heterogeneity and potential biases.

Original Source(s)

What's Heart Disease Got to Do With It?

Large meta-analysis explores how depression, anxiety, PTSD, and sleep disorders affect heart health

  • by Henry Thomas

  • January 27, 2026

  • 3 min

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