Searching for the Spectral Signature of Alzheimer’s
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By
February 6, 2026
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2 min
Recent research from the Istituto Italiano di Tecnologia in Rome highlights a significant advancement in Alzheimer's disease (AD) diagnosis through a novel tri-spectral retinal imaging technique. This method integrates with existing fundus cameras to create an optical biomarker for AD, capturing retinal data across blue, green, and red wavelengths. In a study involving patients with mild AD and healthy controls, the technology demonstrated promising results by highlighting differences in retinal reflectance. Though initial findings are encouraging, further validation is required.
1. Tri-spectral imaging integrates with fundus cameras. 2. It captures data in blue, green, and red bands. 3. Study involved 38 patients with mild AD. 4. Initial results show increased blue reflectance in AD patients. 5. Machine learning model achieved AUC of 0.91. 6. Need for larger validation studies emphasized.
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