Personalizing Corneal Cross-Linking
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By
January 12, 2026
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7 min
Corneal cross-linking (CXL) has transitioned from a standardized protocol to a personalized treatment, aligning with advancements in corneal understanding. This evolution is evident in three clinical scenarios: prioritizing safety in patients with good vision through epi-on CXL; enhancing outcomes in keratoconus cataract patients with corneal optimization; and addressing markedly irregular corneas through customized CXL combined with laser enhancement. Such personalization improves corneal stability and visual quality, reflecting a shift towards tailored ophthalmic care.
- CXL has moved from a fixed to a personalized approach for corneal ectatic diseases.- Epi-on CXL minimizes pain and infection risk while maintaining epithelial integrity.- Corneal optimization improves biometric accuracy in keratoconus patients before cataract surgery.- Customized CXL techniques enhance stability and visual outcomes for irregular corneas.- Current protocols emphasize tailoring treatment to patient-specific needs and circumstances.
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