From the Journals

Oxytocin’s Role in Obesity Management

Researchers review human data on oxytocin’s effects on appetite, satiety, and metabolic health

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Recent systematic review by Abdulrahman A. Alsayegh, PhD, examines oxytocin's effects on appetite and metabolic outcomes in overweight and obese individuals. Analyzing 14 human studies from 2015 to 2025, findings indicate that intranasal oxytocin administration reduced caloric intake and enhanced satiety in short-term studies. However, long-term results showed no significant changes in weight or energy expenditure. The review also suggests oxytocin’s potential metabolic benefits and emphasizes the need for extensive trials to establish its clinical application in obesity management.

Original Source(s)

Oxytocin’s Role in Obesity Management

Researchers review human data on oxytocin’s effects on appetite, satiety, and metabolic health

  • by Jess Allerton

  • January 9, 2026

  • 3 min

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