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Airway Resistome Higher In Chronic Lung Disease

Recent antibiotic exposure was linked to greater antimicrobial resistance gene burden in bronchoscopy samples of patients with chronic lung disease.

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A study found that patients with chronic lung diseases, particularly sarcoidosis and idiopathic pulmonary fibrosis (IPF), show a significantly higher prevalence of antimicrobial resistance (AMR) genes in their lower airway microbiome compared to healthy controls. Analyzing bronchoalveolar lavage samples from 263 participants, researchers discovered that antibiotic exposure increased the likelihood of harboring resistance genes. The cross-sectional design limits causative interpretations, highlighting the need for further investigation into the microbiome's role in antibiotic resistance in lung disease.

Original Source(s)

Airway Resistome Higher In Chronic Lung Disease

  • by Andrea Surnit

  • March 27, 2026

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