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Mass Spec Roundup: Proteoforms, PFAS, and Volatilomics…

  • January 14, 2026

  • 4 min

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Recent studies have unveiled crucial insights into pancreatic cancer's interaction with its microenvironment and potential risks from hazardous substances in firefighting gear. The first study provided a comprehensive analysis of protein conformational changes and phosphorylation in pancreatic ductal adenocarcinoma, identifying key metabolic enzymes linked to drug resistance. Meanwhile, research uncovered alarming contamination with per- and polyfluoroalkyl substances (PFAS) on firefighter gear, underscoring the health risks they pose. Additionally, advancements in using high-resolution gas chromatography have mapped diet-related changes in gut metabolism, enhancing understanding of microbial fermentation and its implications for health.

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