Mass Spec Roundup: Proteoforms, PFAS, and Volatilomics…
January 14, 2026
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4 min
Recent studies have unveiled crucial insights into pancreatic cancer's interaction with its microenvironment and potential risks from hazardous substances in firefighting gear. The first study provided a comprehensive analysis of protein conformational changes and phosphorylation in pancreatic ductal adenocarcinoma, identifying key metabolic enzymes linked to drug resistance. Meanwhile, research uncovered alarming contamination with per- and polyfluoroalkyl substances (PFAS) on firefighter gear, underscoring the health risks they pose. Additionally, advancements in using high-resolution gas chromatography have mapped diet-related changes in gut metabolism, enhancing understanding of microbial fermentation and its implications for health.
1. Study reveals protein changes in pancreatic cancer cell communication. 2. Identification of metabolic enzymes linked to drug resistance. 3. PFAS contamination found on all firefighter protective gear. 4. Non-destructive wipe test detects harmful substances effectively. 5. Gas chromatography method maps diet-related gut changes. 6. Digestive health linked to diet and probiotic use. 7. Research opens pathways for targeted interventions in pancreatic cancer.
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