Solving the Problem of Insolubility: Part II
KinetiSol’s solvent-free mixing process turns “brick dust” drugs into stable amorphous dispersions
In a discussion led by CEO Elizabeth Hickman and CSO Dave Miller of Austin Px, the focus is on the innovative KinetiSol technology, which addresses solubility challenges in drug formulation. Initially aimed at enhancing manufacturing efficiency, KinetiSol targets 'brick dust molecules,' which are largely insoluble and unmet by traditional methods. This technology leverages mechanical energy and excipient-based solvents to create improved drug delivery systems, enhancing solubility and speeding up the process, marking a significant advancement in pharmaceutical manufacturing.
1. KinetiSol technology focuses on solubility challenges in drug formulation. 2. It targets 'brick dust molecules' that are poorly soluble. 3. The process uses excipients as solvents without organic solvents. 4. It generates a malleable mass through mechanical energy. 5. Final products are dense, free-flowing particles. 6. Developed from insights in plastics mixing technology. 7. Designed for efficiency in pharmaceutical manufacturing.