Gut Bacteria Linked to Insulin Resistance
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By
November 12, 2024
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2 min
The study, published in Gut, revealed consistent associations between gut Proteobacteria, notably from the Enterobacteriaceae family, and reduced insulin sensitivity. The research, conducted across multiple cohorts, also highlighted negative correlations between deoxycholic acid (DCA) levels and insulin sensitivity, as well as the impact of T-cell–related signatures on insulin sensitivity in both the intestine and adipose tissue. Moreover, the study underscored the link between Drosophila melanogaster models, high-fat diet, and Enterobacter cloacae colonization and their relevance to insulin resistance. Led by researchers from various institutions, this work provided new insights into the intricate relationship between gut microbiota, immune responses, and metabolic health.
1. Gut Proteobacteria associated with reduced insulin sensitivity2. Negative correlations between deoxycholic acid levels and insulin sensitivity3. Impact of T-cell–related signatures on insulin sensitivity in intestines and adipose tissue4. Relevance of Drosophila melanogaster models and high-fat diet to insulin resistance5. Research offers new insights into gut microbiota, immune responses, and metabolic health
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