Clinical Guidelines

Blood Test Forecasts Alzheimer's Onset

Plasma p-tau217 “clocks” estimate timing of symptoms years before clinical diagnosis

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  • March 9, 2026

  • 2 min

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A study published in Nature Medicine reveals that phosphorylated tau217 levels in blood can predict the onset of symptomatic Alzheimer’s disease years prior to memory issues. Researchers developed statistical models that utilize longitudinal p-tau217 measurements to create disease clocks, estimating when cognitive symptoms may emerge. This method enhances accessibility compared to PET imaging, as p-tau217 levels rise progressively with disease progression. Lead researcher Suzanne Schindler emphasizes the potential for these blood tests to inform future treatment and prevention strategies.

Original Source(s)

Blood Test Forecasts Alzheimer's Onset

Plasma p-tau217 “clocks” estimate timing of symptoms years before clinical diagnosis

  • March 9, 2026

  • 2 min

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