From the Journals

Can CT Radiomics Detect Osteoporosis?

Radiomics analysis of lumbar spine computed tomography is compared with established imaging-based measures of bone density.

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A machine-learning radiomics model developed from lumbar spine CT scans has demonstrated superior performance in detecting osteoporosis compared to traditional vertebral bone quality scoring and Hounsfield unit measurement. This retrospective analysis involved 166 patients who underwent dual-energy X-ray absorptiometry and imaging studies between January 2020 and June 2023. The XGBoost model achieved an area under the curve of 0.91 in the test cohort, with high sensitivity and specificity, establishing its potential as an effective screening tool for osteoporosis, although further multicenter validation is required.

Original Source(s)

Can CT Radiomics Detect Osteoporosis?

Radiomics analysis of lumbar spine computed tomography is compared with established imaging-based measures of bone density.

  • by Kathryn Wighton

  • February 24, 2026

  • 3 min

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