From the Journals

USO Tied to Lower HGSC Risk, Study Shows

Researchers assess whether unilateral salpingo-oophorectomy before age 50 lowers cancer risk without raising cardiovascular or bone complications.

Share

A retrospective cohort study published in PLOS Medicine indicates that women who underwent unilateral salpingo-oophorectomy (USO) have a 36% lower risk of developing high-grade serous ovarian cancer compared to matched controls. This research, led by Dr. Huan Yi, involved 42,306 women from Swedish registries between 1993 and 2018. Importantly, USO did not increase risks for coronary artery disease or osteoporosis, making it a favorable option for premenopausal women. The study suggests that USO is a viable alternative to bilateral salpingo-oophorectomy for cancer prevention without compromising bone and cardiovascular health.

Original Source(s)

USO Tied to Lower HGSC Risk, Study Shows

Researchers assess whether unilateral salpingo-oophorectomy before age 50 lowers cancer risk without raising cardiovascular or bone complications.

  • by Stanley Gajete

  • August 20, 2025

  • 3 min

Related Content

AI-Supported Mammography in MASAI Study

AI-supported mammography screening led to fewer interval and invasive cancers, strengthening the case for clinical adoption, researchers report.

HRSA Adds Self-Collection to Screening

Updated guidelines position patient-collected testing as an option for patients aged 30 to 65 years who are at average risk of cervical cancer, with mandatory insurance coverage beginning January 2027

At-Home HPV Test Matches Clinic Accuracy

Researchers found that an at-home self-collection device for HPV testing demonstrated high accuracy and safety, matching clinician-collected results for cervical cancer screening.