CRC Risk: Comparing BMI with Central Obesity Metrics
January 24, 2025
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2 min
A recent study analyzing data from the UK Biobank cohort revealed that central obesity measures, such as waist circumference and waist-to-hip ratio, show higher risks for colorectal cancer compared to body mass index. The analysis emphasized the significance of incorporating waist circumference and waist-to-hip ratio into clinical and public health approaches for colorectal cancer prevention, as reliance on body mass index alone may underestimate the obesity-related burden of colorectal cancer. Lead study author, Fatemeh Safizadeh, and colleagues concluded that central obesity measures more comprehensively reflect the risk of colorectal cancer attributable to excess weight.
1. Central obesity measures, like waist circumference and waist-to-hip ratio, demonstrate higher risks for colorectal cancer compared to body mass index. 2. Incorporating waist circumference and waist-hip ratio into clinical and public health approaches for colorectal cancer prevention is crucial. 3. The study utilized data from 458,543 patients aged 40 to 69 years from the UK Biobank cohort. 4. Lead study author is Fatemeh Safizadeh from the German Cancer Research Center and Heidelberg University. 5. Hazard ratios were stronger for central obesity metrics compared to BMI for colorectal cancer. 6. The study emphasizes the inadequacy of relying on BMI alone for assessing colorectal cancer risk. 7. Using only BMI may underestimate the obesity-related burden of colorectal cancer.
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