Cause of chronic diarrhoea - Takeaway - MDSpire

Cause of chronic diarrhoea

Share

  • 1

    A 52-year-old man presented with chronic diarrhea and significant weight loss, leading to a BMI of 14.9 kg/m².

  • 2

    Laboratory tests indicated anemia, low serum protein, and elevated IgM and β2-microglobulin levels.

  • 3

    Histological examination revealed marked villous blunting and dilated lymphatic vessels in the terminal ileum.

  • 4

    The diagnosis was Waldenström’s macroglobulinaemia with intestinal lymphangiectasia, confirmed by immunophenotyping and genetic testing.

  • 5

    Treatment with the RCD regimen resulted in improved symptoms and nutritional status, with significant regression of intestinal lesions.

Original Source(s)

Related Content