Effect of a 5:2 intermittent fasting diet on obese patients with polycystic ovary syndrome

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  • 1

    The study investigates the effects of a 12-week 5:2 intermittent fasting diet with meal replacement on obese women with PCOS.

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    Participants in the intervention group experienced significant reductions in body weight, waist circumference, and BMI.

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    Insulin resistance decreased significantly in the intervention group, along with improvements in fasting glucose levels.

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    Menstrual regularity improved in 80% of participants, and 50% showed enhanced ovulation frequency despite no significant changes in reproductive hormones.

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    The findings suggest that the 5:2 intermittent fasting diet with meal replacement is effective for improving metabolic markers in obese women with PCOS.

Original Source(s)

Effect of a 5:2 intermittent fasting diet on obese patients with polycystic ovary syndrome

  • by Wencheng An, Fang Chen, Bingyan Wang, Shujing Zhou, Lin Jiang, Bo An, Zhijun Cui, Xiaohong Ou, Wei Huang, Huixian Yan

  • March 18, 2026

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