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Maternal and neonatal vitamin D metabolite profiling and its long-term impact on childhood growth: findings from the KLOTHO birth cohort

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  • 1

    Vitamin D plays a crucial role in growth, metabolism, and body composition during early life, impacting long-term health outcomes.

  • 2

    The KLOTHO cohort study analyzed eight vitamin D metabolites in cord blood to explore their associations with childhood growth.

  • 3

    Preliminary trends indicated that D3-related metabolites may correlate with linear growth and adiposity measures in children.

  • 4

    None of the associations reached statistical significance after multiple testing corrections, highlighting the exploratory nature of the findings.

  • 5

    The study emphasizes the need for larger longitudinal studies to better understand the role of vitamin D metabolism in childhood growth.

Original Source(s)

Maternal and neonatal vitamin D metabolite profiling and its long-term impact on childhood growth: findings from the KLOTHO birth cohort

  • by Spyridon N. Karras, Maria Kypraiou, Vikentia Harizopoulou, Antonios Vlastos, Marios Anemoulis, Maria Dalamaga, Neoklis Georgopoulos, Evanthia Kassi, Georgios Mastorakos, Kali Makedou, Dimitrios Skoutas, Melpomeni Peppa, Dimitrios G. Goulis

  • March 25, 2026

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