Ejaculation-preserving holmium laser enucleation of the prostate: a systematic review of techniques, functional outcomes, and safety

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  • 1

    Holmium laser enucleation of the prostate (HoLEP) is a guideline-endorsed surgical standard for benign prostatic hyperplasia (BPH) with low retreatment rates.

  • 2

    Conventional HoLEP is associated with high rates of retrograde ejaculation, prompting the need for techniques that preserve antegrade ejaculation.

  • 3

    Anatomical studies suggest that preserving peri-verumontanum and bladder-neck structures is crucial for maintaining ejaculatory function post-surgery.

  • 4

    Various ejaculation-preserving modifications of HoLEP have been proposed, each differing in tissue preservation and potential impact on ejaculatory function.

  • 5

    A systematic review of ejaculation-preserving HoLEP techniques aims to compare outcomes related to antegrade ejaculation and urinary function.

Original Source(s)

Ejaculation-preserving holmium laser enucleation of the prostate: a systematic review of techniques, functional outcomes, and safety

  • by Mehmet Hamza Gultekin, Kadir Can Sahin, Admir Ozturk, Feyyaz Irmak, Bulent Onal

  • March 21, 2026

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