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From the Journals

New Histology Signal in Crohn’s

  • March 26, 2026

  • 2 min

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  • 1

    Fibrostenosing Crohn's disease characterized by bowel wall thickening.

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    Submucosal scarring is a defining feature.

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    Endothelial cell clusters found within lymphoid aggregates.

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    Spatial analysis links clusters to fibrosis.

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    Higher fibrosis scores associated with endothelial clusters.

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    Study improves understanding of tissue remodeling in Crohn's disease.

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    Insights may aid in diagnosing fibrostenosing Crohn's patients.

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