Putting a POC Troponin to the Test
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By
February 5, 2026
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3 min
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1
The study verified the hs-TnI assay's precision and analytical performance.
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2
Intra-assay CVs ranged from 2.8% to 15.9%.
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3
Hemolysis interference was minimal up to 10 g/L.
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4
Correlation coefficients with other assays were as high as 0.
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5
The assay performs adequately for diagnosing myocardial infarction in various settings.
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6
Limitations included logistical constraints in sample collection.
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7
Recommendations support integration into emergency care pathways.
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A multicenter study confirmed the reliability of the QuidelOrtho TriageTrue high-sensitivity troponin I (hs-TnI) assay, demonstrating acceptable precision and minimal interference with analytical performance. The assessment involved 200 samples measuring concordance against laboratory assays. Results revealed intra-assay precision coefficients of variation (CV) between 2.8% and 15.9% at varying troponin levels, with correlations up to 0.99, indicating strong performance for myocardial infarction diagnosis in clinical settings. Further validation supports its integration into emergency protocols.
-
1
The study verified the hs-TnI assay's precision and analytical performance.
-
2
Intra-assay CVs ranged from 2.8% to 15.9%.
-
3
Hemolysis interference was minimal up to 10 g/L.
-
4
Correlation coefficients with other assays were as high as 0.
-
5
The assay performs adequately for diagnosing myocardial infarction in various settings.
-
6
Limitations included logistical constraints in sample collection.
-
7
Recommendations support integration into emergency care pathways.
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