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Neurofilament Levels Linked to AF Risk

Higher levels associated with stroke, death, and heart failure in long-term cohort

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  • 1

    Higher serum NfL levels correlate with increased vascular event risk.

  • 2

    Each doubling of NfL is associated with 35% higher major event risk.

  • 3

    Patients without anticoagulation exhibit stronger risk association.

  • 4

    Heart failure hospitalizations and all-cause mortality rise with NfL levels.

  • 5

    Study includes 2,311 AF patients from Swiss centers.

  • 6

    Observational nature limits causal conclusions.

  • 7

    NfL could serve as a noncardiac biomarker for AF patients.

Original Source(s)

Neurofilament Levels Linked to AF Risk

  • by Andrea Surnit

  • March 30, 2026

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