From the Journals

Frailty Linked to Higher Mortality Risk in Men Than Women After Heart Attack

National study of more than 900,000 patients finds frailty more prevalent in women but more strongly associated with death in men, highlighting a “sex-frailty paradox” in outcomes.

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    Study involved over 931,000 patients with AMI from 2005-

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    Frailty assessed using SCARF index.

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    34.1% of patients were female.

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    Higher prevalence of severe frailty in women (16.7%).

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    Male patients have higher mortality rates associated with frailty.

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    Suggests a need for integrated clinical evaluations considering frailty and sex.

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    Results challenge traditional risk assessment approaches.

Original Source(s)

Frailty Linked to Higher Mortality Risk in Men Than Women After Heart Attack

National study of more than 900,000 patients finds frailty more prevalent in women but more strongly associated with death in men, highlighting a “sex-frailty paradox” in outcomes.

  • by Olivia Anderson

  • March 2, 2026

  • 3 min

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