From the Journals

Hot Springs Yield Robust Enzymes for Molecular Diagnostics

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  • February 18, 2026

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  • 1

    UvsXt and UvsXp are bacteriophage recombinases from extreme environments.

  • 2

    UvsXt shows higher thermal stability than UvsXp.

  • 3

    Both enzymes are similar to RecA-family recombinases.

  • 4

    UvsXp performed better than E. coli RecA in strand exchange assays.

  • 5

    UvsXt improved sensitivity in RT-LAMP assays.

  • 6

    Both enzymes retain unique functional characteristics.

  • 7

    Potential applications in rapid viral RNA detection diagnostics.

  • 8

    Further validation is needed for clinical use.

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