PsA Treatment Options Expand
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By
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March 9, 2026
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3 min
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1
Deucravacitinib (Sotyktu) is now FDA approved for active psoriatic arthritis.
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It is the first TYK2 inhibitor for this indication.
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Phase 3 trials showed significant improvements versus placebo.
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ACR20 response was 54% in two trials.
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Common adverse effects include respiratory infections and herpes simplex.
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The drug targets TYK2 pathways involved in inflammation.
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Patients had documented plaque psoriasis.
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Treatment improves disease activity and response rates.