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GLP-1 Analysis: Riding the Wave of Peptide Innovation

The remarkable commercial success of GLP-1 receptor agonists is fueling investment, accelerating science, and creating new analytical challenges. Here, we outline the hurdles these peptides present, explore methods for impurity profiling and structural characterization, and consider strategies to keep pace with this fast-moving field.

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  • 1

    GLP-1 receptor agonists are effective for diabetes & weight loss.

  • 2

    Innovations include oral formulations and multi-agonist therapies.

  • 3

    Impurity profiling is crucial to ensure safety & efficacy.

  • 4

    Advanced analytics are needed for complex peptide therapeutics.

  • 5

    Market demand is increasing, leading to drug counterfeiting concerns.

Original Source(s)

GLP-1 Analysis: Riding the Wave of Peptide Innovation

The remarkable commercial success of GLP-1 receptor agonists is fueling investment, accelerating science, and creating new analytical challenges. Here, we outline the hurdles these peptides present, explore methods for impurity profiling and structural characterization, and consider strategies to keep pace with this fast-moving field.

  • by Amanda M. Guiraldelli, Piotr Alvarez, Koen Sandra

  • January 26, 2026

  • 17 min

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