From the Journals

PPIs Linked to Worse Breast Cancer Outcomes

Pooled analysis of nearly 23,000 patients shows medication commonly used for acid reflux may interfere with cancer treatment effectiveness.

Share

5 Key Takeaways

  • 1

    Study involved 23,211 breast cancer patients from 19 trials.

  • 2

    PPI use linked to worse overall survival and higher adverse events.

  • 3

    Researchers explored the impact of gut microbiota on immune response.

  • 4

    Limitations included observational data and missing details on PPI use.

  • 5

    Emphasizes careful management of concomitant medications in breast cancer treatment.

Original Source(s)

PPIs Linked to Worse Breast Cancer Outcomes

Pooled analysis of nearly 23,000 patients shows medication commonly used for acid reflux may interfere with cancer treatment effectiveness.

  • by Mouj Hijazi

  • November 18, 2025

  • 3 min

Related Content

Could AI Unlock Mass Spectrometry’s Full Discovery Potential?

Self-supervised learning models – such as Matterwork’s Large Spectral Model – turn raw spectra into biological insight in minutes

  • November 11, 2025

  • 9 min
The Sepapure Solution

Dr. Kristin Folmert, Analytical Product Manager at KNAUER, showcases how Sepapure oliGO is raising the bar for affordable, high-performance oligonucleotide analysis

  • November 11, 2025

  • 5 min
Ion Mobility's Innovation Explosion

Recent advances in trapped, traveling-wave, and SLIM platforms are unlocking ion mobility’s full potential across proteomics, metabolomics, and structural biology