Chronic Cough Despite Normal Workup
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By
February 13, 2026
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2 min
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1
Patient: Middle-aged woman with 3-month dry cough.
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2
Unresponsive to inhalers and OTC suppressants.
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3
Normal imaging and pulmonary tests.
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4
Diagnosed with cough-predominant laryngeal hypersensitivity syndrome.
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5
Key finding: bronchoscopy highlighted laryngeal hypersensitivity.
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6
Emphasizes multidisciplinary management strategies.
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7
Raises awareness for unexplained chronic cough cases.
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8
Lead author: Muhammad Ammar Iqbal, University Hospital Limerick.
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A middle-aged woman experienced a persistent dry cough for three months, unresponsive to treatments and with normal chest imaging and pulmonary function tests. Despite these results, her cough worsened, disrupting daily life. Evaluations revealed marked laryngeal hypersensitivity, leading to a diagnosis of cough-predominant laryngeal hypersensitivity syndrome, a sensory disorder characterized by heightened cough reflex responsiveness. Management included a multidisciplinary approach focusing on education and behavioral techniques. Muhammad Ammar Iqbal from the University Hospital Limerick emphasizes the need for awareness of this syndrome in cases of unexplained chronic cough.
-
1
Patient: Middle-aged woman with 3-month dry cough.
-
2
Unresponsive to inhalers and OTC suppressants.
-
3
Normal imaging and pulmonary tests.
-
4
Diagnosed with cough-predominant laryngeal hypersensitivity syndrome.
-
5
Key finding: bronchoscopy highlighted laryngeal hypersensitivity.
-
6
Emphasizes multidisciplinary management strategies.
-
7
Raises awareness for unexplained chronic cough cases.
-
8
Lead author: Muhammad Ammar Iqbal, University Hospital Limerick.
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