From the Journals

Parkinson's Aggravated by Nanoplastics Exposure

Mouse study suggests environmental nanoplastics may exacerbate Parkinson's disease through metabolic dysregulation in the gut, brain, and liver

Share

  • 1

    - Chronic polystyrene nanoplastics exposure was studied in A53T α-synuclein mice. - Significant gastrointestinal changes included fewer mucus-producing cells and increased gut lining cell death. - Altered gut microbiota showed an increase in Desulfovibrio bacteria. - Metabolomic profiling revealed over 200 altered metabolites linked to inflammatory processes. - Liver inflammation was noted, but cell death levels remained unchanged. - Elevated inflammatory markers were detected in the brain tissue.

Original Source(s)

Parkinson's Aggravated by Nanoplastics Exposure

Mouse study suggests environmental nanoplastics may exacerbate Parkinson's disease through metabolic dysregulation in the gut, brain, and liver

  • by Kathryn Wighton

  • January 27, 2026

  • 2 min

Related Content

How Metal Imbalance Rewires Metabolism 

Integrated metallomics and metabolomics map metabolic responses to metal imbalance

  • February 25, 2026

  • 2 min
Genetic Mutations in ANO3 Linked to Dystonia

Dysregulated Ca²⁺ signaling due to ANO3 mutations impairs K⁺ channel activation in striatal neurons, offering new insights into the pathophysiology of dystonia.

AI in Neuropathology: How Language Models Are Transforming Brain Tumor Diagnosis

New research explores how integrating AI with clinical guidelines can enhance diagnostic precision for complex brain tumors.