From the Journals

Proton Pump Inhibitors and Cancer Risk

Investigators evaluate cancer risk tied to extended acid suppression therapy.

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  • 1

    Study examined link between PPIs and gastric non-cardia adenocarcinoma.

  • 2

    Included over 17,000 patients from Nordic countries.

  • 3

    Adjusted for multiple health factors including obesity and medications.

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    No significant risk found after adjustments.

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    Observational design may have residual confounding.

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    Dietary factors and some rare conditions were not included.

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    Research funded by notable Swedish organizations.

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    Author emphasizes importance of bias prevention measures.

Original Source(s)

Proton Pump Inhibitors and Cancer Risk

Investigators evaluate cancer risk tied to extended acid suppression therapy.

  • by Kathryn Wighton

  • February 19, 2026

  • 3 min

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