From the Journals

Positive Urine Cytology Reveals Melanoma

Rare case links prior melanoma in situ to ureter and porta hepatis metastases

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  • 1

    Metastatic melanoma can occur years after melanoma in situ excision.

  • 2

    Atypical genitourinary lesions should include metastatic melanoma in differential diagnosis.

  • 3

    Immunohistochemical evaluation is critical for accurate diagnosis.

  • 4

    Ureteral involvement in melanoma is rare (0.2% to 1%).

  • 5

    Patient was treated with pembrolizumab after diagnosis of metastatic melanoma.

Original Source(s)

Positive Urine Cytology Reveals Melanoma

Rare case links prior melanoma in situ to ureter and porta hepatis metastases

  • by Jess Allerton

  • February 16, 2026

  • 3 min

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