Nano-IR Spectroscopy Maps Molecules Inside Living Cells
November 6, 2025
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2 min
7 Key Takeaways
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1
Nano-IR spectroscopy technique developed for imaging living cells.
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Overcomes limitations of imaging hydrated systems.
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Uses an ultra-thin silicon carbide membrane for imaging.
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Enabled by the IRIS beamline at BESSY II synchrotron.
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Allows detailed analysis of proteins, nucleic acids, and membrane lipids.
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Spatial resolution achieved below 10 nm.
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Potential applications in studying cancer and disease processes under native conditions.
Researchers have developed a pioneering nano-infrared (nano-IR) spectroscopy technique to visualize the molecular composition of living animal cells in their natural liquid environment. This study, led by Alexander Veber from Helmholtz-Zentrum Berlin, marks a significant advancement in biological imaging. Utilizing the IRIS beamline at the BESSY II synchrotron source, the technique involves an ultra-thin silicon carbide membrane to enhance imaging capabilities, allowing for detailed analysis of cellular components, which can transform research in cancer and disease processes.
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