Folate: A Shield Against Lead's Impact?
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By
October 16, 2024
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2 min
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1
Association between gestational blood lead levels and autistic-like behaviors in preschool-age children\n
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Stronger association observed with lower maternal folate levels\n
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Potential benefits of folic acid supplementation in mitigating lead exposure effects\n
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4
The study involved 601 mother-child pairs from the MIREC study\n
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5
Assessment of autistic-like behaviors conducted using the Social Responsiveness Scale-2 (SRS-2)\n
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6
Mention of potential influence of MTHFR genotype on the associations\n
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7
Study limitations include participant demographics and residual confounding
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A study from Canada revealed an association between gestational blood lead levels and autistic-like behaviors in preschool-age children, particularly pronounced in cases with lower maternal folate levels. The research, conducted with 601 mother-child pairs, highlighted that third-trimester blood lead levels were linked to increased SRS-2 scores among participants with low plasma total folate concentrations. Moreover, the study indicated potential benefits of folic acid supplementation in mitigating the effects of lead exposure during pregnancy.
-
1
Association between gestational blood lead levels and autistic-like behaviors in preschool-age children\n
-
2
Stronger association observed with lower maternal folate levels\n
-
3
Potential benefits of folic acid supplementation in mitigating lead exposure effects\n
-
4
The study involved 601 mother-child pairs from the MIREC study\n
-
5
Assessment of autistic-like behaviors conducted using the Social Responsiveness Scale-2 (SRS-2)\n
-
6
Mention of potential influence of MTHFR genotype on the associations\n
-
7
Study limitations include participant demographics and residual confounding
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