MDSpire - Takeaway
From the Journals

Could NPDR Be Treated Orally?

  • March 24, 2026

  • 5 min

Share

  • 1

    Danegaptide is an oral drug for non-proliferative diabetic retinopathy.

  • 2

    The phase 1b trial involved 24 patients across 11 sites.

  • 3

    It aims to stabilize gap-junctions and counter VEGF effects.

  • 4

    The trial met objectives of safety, tolerability, and showed early signs of effectiveness.

  • 5

    Orally administered treatments may improve patient adherence.

  • 6

    It addresses significant unmet needs in earlier stages of diabetic retinopathy.

  • 7

    Potential to reduce treatment burden from repeated injections.

Original Source(s)

Related Content