From the Journals

Apocrine Gland Changes in Early Hidradenitis Suppurativa

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  • 1

    Study in the Journal of Investigative Dermatology identifies apocrine gland damage and keratin release in HS pathogenesis.

  • 2

    Significant reduction in apocrine gland size observed in LS and NLS compared with healthy controls.

  • 3

    Histologic analysis showed severe degeneration in LS and NLS apocrine glands.

  • 4

    Elevated levels of keratins KRT18 and KRT19 observed in patients with HS.

  • 5

    AG dysfunction and keratin release may contribute to early inflammatory processes in HS.

  • 6

    Potential biomarkers for HS severity and progression.

  • 7

    Associations between serum KRT19 levels and age at disease onset.

  • 8

    Further research needed to validate the clinical utility of identified biomarkers.

Original Source(s)

Apocrine Gland Changes in Early Hidradenitis Suppurativa

  • by Kathryn Wighton

  • November 18, 2024

  • 2 min

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