From the Journals

Trial Tests Timing of IOPTH in RHPT Surgery

About 15% of patients with parathyroid gland enlargement from chronic kidney disease still require surgery within 10 years of starting dialysis, even with calcimimetics treatment. Surgical failure rates can reach 28%, often due to missed ectopic or supernumerary glands.

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  • 1

    Trial assesses IOPTH monitoring during parathyroidectomy.

  • 2

    Targets 60 patients at high-volume centers.

  • 3

    Measures feasibility of randomization and patient recruitment.

  • 4

    Evaluates surgical success and complications over 6 months.

  • 5

    Enrollment started February 2025, reporting expected 2027.

Original Source(s)

Trial Tests Timing of IOPTH in RHPT Surgery

About 15% of patients with parathyroid gland enlargement from chronic kidney disease still require surgery within 10 years of starting dialysis, even with calcimimetics treatment. Surgical failure rates can reach 28%, often due to missed ectopic or supernumerary glands.

  • by Stanley Gajete

  • August 15, 2025

  • 3 min

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