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1
VCTE provides equivalent prognostic accuracy to liver biopsy.
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2
Study involved 3,532 patients with MASLD.
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3
3.6% of patients developed liver-related events after 56.6 months.
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4
Median baseline liver stiffness measurement was 8.8 kPa.
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5
Both methods showed nearly identical performance metrics.
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6
LSM may serve as a practical alternative for histology in clinical trials.
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Vibration-controlled transient elastography (VCTE) for liver stiffness measurement (LSM) demonstrates comparable prognostic accuracy to liver biopsy for predicting liver-related events (LREs) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). A study involving 3,532 adults indicated that LSM is strongly associated with liver events, with a mean baseline LSM of 8.8 kPa among studied patients. After a median follow-up of 56.6 months, both methods yielded similar performance metrics, suggesting LSM may serve as a practical surrogate for histology in clinical settings.
-
1
VCTE provides equivalent prognostic accuracy to liver biopsy.
-
2
Study involved 3,532 patients with MASLD.
-
3
3.6% of patients developed liver-related events after 56.6 months.
-
4
Median baseline liver stiffness measurement was 8.8 kPa.
-
5
Both methods showed nearly identical performance metrics.
-
6
LSM may serve as a practical alternative for histology in clinical trials.
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