Vitamin D Multifaceted CRC Immunomodulator Revealed
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by Kerri Miller
April 24, 2025
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4 min
5 Key Takeaways
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1
Vitamin D has a potential role in preventing colorectal cancer by regulating immune system & inducing anticancer mechanisms.
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2
Higher vitamin D levels are associated with a lower risk of colorectal cancer.
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3
Supplementation of 2000 IU/day is recommended for adults.
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4
A nutrient-dense diet is crucial for reducing CRC risk.
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5
Further randomized clinical trials are needed to define optimal supplementation protocols.
A comprehensive review outlines vitamin D's potential role in preventing colorectal cancer through immunological and inflammatory pathways. With evidence from over 50 cohort studies, it suggests that vitamin D regulates immune system, suppresses inflammation, and induces anticancer mechanisms. Higher vitamin D levels are associated with a lower risk of colorectal cancer, and supplementation is recommended for at-risk populations.
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