From the Journals

What Shapes Pediatric Platelet Response?

REDS-IV-P data examine how storage time, pathogen reduction, and donor factors affect transfusion outcomes in pediatric patients

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  • 1

    The study analyzed 249,340 inpatient encounters from April 2019 to June

  • 2

    Median age of transfused patients was 2.5 years.

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    32.5% of transfusions occurred within six hours of other transfusions.

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    Factors like PAS and donor age affected platelet increment outcomes.

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    Median transfusion dose was 14.9 mL/kg in neonates and 9.6 mL/kg in older children.

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    No donor characteristics influenced hospital length of stay or mortality.

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    Variability in transfusion thresholds highlights need for clinical context in decisions.

Original Source(s)

What Shapes Pediatric Platelet Response?

REDS-IV-P data examine how storage time, pathogen reduction, and donor factors affect transfusion outcomes in pediatric patients

  • by Jess Allerton

  • February 26, 2026

  • 3 min

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