From the Journals

Mediastinitis Carries Highest Death Risk Postsurgery

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  • 1

    Severe chest bone infections, especially mediastinitis, were significantly associated with increased mortality within 90 days in patients who underwent cardiac surgery.

  • 2

    Deep incisional surgical-site infections also posed an elevated mortality risk.

  • 3

    Both mediastinitis and deep incisional surgical-site infections should be monitored separately for improved patient survival.

  • 4

    Mediastinitis typically developed 14 days postsurgery and was associated with distinct pathogens and outcomes compared to diSSI.

  • 5

    Closer monitoring and prompt, aggressive treatment of both infection types may improve survival in patients undergoing cardiac surgery.

  • 6

    Risk factors for 90-day mortality included age over 56 years, insulin-dependent diabetes, peripheral arterial disease, prior cardiac surgery, emergency procedures, end-stage renal disease, reduced ejection fraction, and longer cardiopulmonary bypass duration.

  • 7

    Study author recommended closer monitoring and aggressive treatment for both infection types to improve survival in patients undergoing cardiac surgery.

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