From the Journals

AF Stroke Prevention: Testing Ablation

In the randomized STABLED trial, adding catheter ablation to edoxaban did not reduce recurrent stroke or major cardiovascular outcomes.

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    Study tested catheter ablation alongside edoxaban in atrial fibrillation patients post-stroke.

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    No significant difference in stroke or cardiovascular outcomes was found.

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    251 participants enrolled from 45 centers in Japan.

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    Follow-up lasted over 3 years.

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    Ablation group suffered more bleeding events, including major bleeding.

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    Low recurrent ischemic stroke rates in standard therapy hindered statistical power.

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    Findings suggest limited benefit of ablation in this cohort.

Original Source(s)

AF Stroke Prevention: Testing Ablation

  • by Kathryn Wighton

  • March 16, 2026

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