NGS Streamlines Clonal Detection in Plasma Cells

10 Key Takeaways

• 1

  NGS improves early detection of MGUS and SMM.

• 2

  Eliminates need for CD138 selection.

• 3

  9

• 4

  1% sensitivity in identifying clonal populations.

• 5

  Study conducted by Columbia University and Tufts University.

• 6

  Highlights importance of early detection for preventing AL amyloidosis.

• 7

  High concordance (9

• 8

  3%) with traditional Sanger sequencing.

• 9

  Streamlines sample processing in clinical labs.

• 10

  Potential impact on patient management in hematology.