FDA & Government News

ALS Drug Misses Trial Goals

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  • 1

    Dazucorilant, an experimental drug by Corcept Therapeutics, did not meet the main goal of slowing the decline in motor skills and functional criteria for ALS patients in a mid-stage trial.

  • 2

    Patients receiving dazucorilant experienced more gastrointestinal upset than those receiving the placebo.

  • 3

    No deaths were observed in the 300 mg dose group of dazucorilant, while five deaths were reported in the placebo group.

  • 4

    Complete study results will be presented next year.

  • 5

    An open-label, long-term extension study will continue, assessing overall survival in March 2025.

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