From the Journals

Comparing Brain Stimulation Strategies for Depression

Two transcranial magnetic stimulation protocols produced different short-term outcomes in patients with major depressive disorder

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  • 1

    iTBS outperformed sequential rTMS in reducing depression.

  • 2

    106 participants completed the trial.

  • 3

    iTBS targeted the left dorsolateral prefrontal cortex.

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    Mean HAMD score dropped by 14.88 points in iTBS vs. 7.88 in rTMS.

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    Both groups tolerated the treatments well, with mild side effects.

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    Cognitive reappraisal improved more significantly with iTBS.

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    Further studies needed to explore long-term outcomes.

Original Source(s)

Comparing Brain Stimulation Strategies for Depression

Two transcranial magnetic stimulation protocols produced different short-term outcomes in patients with major depressive disorder

  • by Henry Thomas

  • March 5, 2026

  • 3 min

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