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1
ERCP with miES does not show benefit in preventing acute pancreatitis in pancreas divisum patients.
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2
Study found no significant difference in acute pancreatitis recurrence, pancreas-related pain, and chronic pancreatitis between miES and sham procedure group.
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3
Risks of ERCP include acute pancreatitis in 10%–20% of patients and papillary stenosis.
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4
Current treatment guidelines for pancreas divisum may be influenced by the study results.
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5
Patients with ductal strictures or obstruction were excluded from the trial.
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A new study has found that endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy (miES) does not provide any benefit in preventing acute pancreatitis in patients with pancreas divisum. Despite prior retrospective studies suggesting its effectiveness, the randomized trial showed no significant difference in acute pancreatitis recurrence, pancreas-related pain, chronic pancreatitis, diabetes, or exocrine pancreatic insufficiency between the miES and sham procedure group. These findings challenge the long-standing advocacy for this intervention and are likely to impact current treatment guidelines.
-
1
ERCP with miES does not show benefit in preventing acute pancreatitis in pancreas divisum patients.
-
2
Study found no significant difference in acute pancreatitis recurrence, pancreas-related pain, and chronic pancreatitis between miES and sham procedure group.
-
3
Risks of ERCP include acute pancreatitis in 10%–20% of patients and papillary stenosis.
-
4
Current treatment guidelines for pancreas divisum may be influenced by the study results.
-
5
Patients with ductal strictures or obstruction were excluded from the trial.
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