Clinical Guidelines

Biochemical Tumor Markers: Are New Testing Guidelines Fit for Purpose?

CLSI guidance achieves technical excellence but has some questionable omissions, says Mustafa Barbhuiya

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  • 1

    CLSI C65 provides guidelines for ten biochemical tumor markers.

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    Focus centers on reducing laboratory errors, especially in pre-examination.

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    Key markers include PSA, CEA, and CA

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    Significant omission of serum free light chains.

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    No specific guidance on radiation therapy monitoring results.

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    Future editions should integrate molecular techniques.

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    Emphasizes creation of a multi-modal oncology framework.

Original Source(s)

Biochemical Tumor Markers: Are New Testing Guidelines Fit for Purpose?

  • by Mustafa Barbhuiya

  • March 18, 2026

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