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1
MACRO trial compared ESS, clarithromycin, and placebo for CRS.
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2
Conducted in 21 ENT centers in England and Scotland.
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3
Interviewed 20 patients and 17 clinicians about treatment experiences.
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4
ESS provided faster symptom relief compared to other treatments.
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5
Patient concerns included risks of surgery and recovery time.
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6
Clariathromycin had limited benefit, often linked to gastrointestinal symptoms.
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7
Implementation of findings requires effective communication with patients.
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8
Support from health systems essential for surgical care.
Original Source(s)
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