From the Journals

Discovery of Novel Susceptibility Gene May Shed Light on Etiology of Psoriatic Arthritis Mutilans

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4 Key Takeaways
  • 1

    Study published in EMBO Mol Med uncovers genetic mechanisms related to psoriatic arthritis mutilans.

  • 2

    Rare variants in NOX4 gene potentially increase reactive oxygen species (ROS) levels.

  • 3

    NOX4's role in osteoclast differentiation implicated.

  • 4

    Findings could lead to new therapeutic interventions.

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