Rethinking Prehabilitation Before Surgery
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By
February 2, 2026
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4 min
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1
Trial compared personalized vs. standard prehabilitation in surgery prep.
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58 patients participated with significant immune profiling differences.
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3
Personalized prehabilitation improved physical/cognitive function.
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4
Fewer postoperative complications in personalized group (4 vs. 11).
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5
Study highlights need for larger multicenter trials for validation.
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Researchers conducted a randomized clinical trial published in JAMA Surgery, examining immune profiling to explore the differences between personalized and standard prehabilitation approaches before surgery. Findings indicated that personalized interventions linked with remote coaching yielded significant preoperative immune signaling differences and improved functional and cognitive outcomes. Patients receiving personalized prehabilitation showed fewer severe postoperative complications, emphasizing the potential for tailored interventions to enhance surgical readiness. The study calls for larger trials to validate these findings.
-
1
Trial compared personalized vs. standard prehabilitation in surgery prep.
-
2
58 patients participated with significant immune profiling differences.
-
3
Personalized prehabilitation improved physical/cognitive function.
-
4
Fewer postoperative complications in personalized group (4 vs. 11).
-
5
Study highlights need for larger multicenter trials for validation.
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