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Gemcitabine Intravesical System Shows High Disease-Free Survival Rates in BCG-Unresponsive Papillary-Only NMIBC

Monotherapy with a gemcitabine intravesical system demonstrated high disease-free survival rates in patients with bacillus Calmette-Guérin-unresponsive papillary-only high-risk non–muscle-invasive bla...

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  • 1

    TAR-200 offers a new option for BCG-unresponsive NMIBC.

  • 2

    85.3% disease-free survival at 6 months, 69.2% at 18 months.

  • 3

    Well tolerated with mostly grade 1/2 adverse events.

  • 4

    80% of enrolled patients declined cystectomy.

  • 5

    Need for effective bladder-sparing therapies highlighted by absence of approved treatments.

Original Source(s)

Gemcitabine Intravesical System Shows High Disease-Free Survival Rates in BCG-Unresponsive Papillary-Only NMIBC

Monotherapy with a gemcitabine intravesical system demonstrated high disease-free survival rates in patients with bacillus Calmette-Guérin-unresponsive papillary-only high-risk non–muscle-invasive bla...

  • by Chase Doyle

  • February 25, 2026

  • 7 min

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