Skin Fluorescent Imaging Shows High Sensitivity, Specificity for Discriminating Melanoma Lesions - Takeaway - MDSpire
Feature

Skin Fluorescent Imaging Shows High Sensitivity, Specificity for Discriminating Melanoma Lesions

Skin fluorescent imaging demonstrated high sensitivity and specificity for the discrimination of low- and high-risk lesions, showing an alternative, noninvasive approach to melanoma biopsies, accordin...

Share

  • 1

    Skin fluorescent imaging offers an effective noninvasive approach to melanoma diagnosis.

  • 2

    The phase II trial assessed 240 suspicious lesions across the U.S.

  • 3

    Sensitivity was 93% and specificity was 77% at cutoff score

  • 4

    41% of lesions were benign with no dysplasia.

  • 5

    High-grade dysplasia was present in 21% of lesions.

  • 6

    Led by Dr. Douglas Grossman, the trial aims to reduce unnecessary biopsies.

  • 7

    The method targets αvβ3 integrin in the tumor microenvironment.

Original Source(s)

Skin Fluorescent Imaging Shows High Sensitivity, Specificity for Discriminating Melanoma Lesions

  • by The ASCO Post Staff

  • April 6, 2026

Related Content

UVB and Psoriasis: More Than Immunosuppression

UVB's benefits may run deeper than inflammation suppression—cholesterol metabolism could be a key link.

Pathology Machine-Learning Models and Diagnosis of Nonmelanoma Skin Cancers in Resource-Limited Settings

Artificial intelligence (AI) models, which were pretrained on vast data sets, outperformed a standard baseline model in identifying nonmelanoma skin cancers from digital images of tissue samples, base...

Tanning Bed Exposure and Melanoma Risks

Research has elucidated how radiation from tanning beds increases the mutation burden across a broad area of melanocytes, thereby significantly raising the risk of developing melanoma. Findings publis...