IL-17, IL-23 Therapies Lead Psoriasis Care - Takeaway - MDSpire
From the Journals

IL-17, IL-23 Therapies Lead Psoriasis Care

Network meta-analysis suggests higher PASI 90 response rates with biologics vs oral systemic therapies

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  • 1

    Biologics show efficacy in treating moderate to severe plaque psoriasis.

  • 2

    IL-17 inhibitors are the most effective biologics.

  • 3

    PASI 90 represents significant skin clearance.

  • 4

    Serious adverse events are rare across treatments.

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    The analysis focused on short-term outcomes.

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    IL-23 inhibitors demonstrated gradual improvement.

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    Consider oral therapies for certain patients.

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    Long-term effectiveness remains under investigation.

Original Source(s)

IL-17, IL-23 Therapies Lead Psoriasis Care

  • by Andrea Surnit

  • April 12, 2026

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