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1
Unilateral surgery shows a 0.1% risk of contralateral tumors.
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2
Five-year survival rates: unilateral 84%, bilateral 78%.
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3
HPV positivity in 92.6% of patients.
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4
Oropharyngeal hemorrhage: 6% for both procedures.
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5
No significant difference in swallowing outcomes between groups.
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6
The study was retrospective, which introduces potential bias.
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7
Unilateral surgery does not compromise outcomes for HPV-positive patients.
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8
Decision-making should be patient-specific within a multidisciplinary context.
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Unilateral transoral surgery for tonsillar squamous cell carcinoma shows similar survival rates and low contralateral tumor risk compared to bilateral procedures, based on a meta-analysis of 1,486 patients. The study revealed a 0.1% incidence of contralateral tumors in unilateral procedures versus 4% in bilateral cases, with two-year and five-year overall survival rates at 96% and 84% respectively for unilateral surgeries. Complication rates, including oropharyngeal hemorrhage and dependence on feeding tubes, were not significantly different. The findings support a selective surgical approach, especially for HPV-positive patients, although the study acknowledged limitations in data completeness and retrospective design. This research was presented by Dr. Andrew M. Peterson from Washington University School of Medicine.
-
1
Unilateral surgery shows a 0.1% risk of contralateral tumors.
-
2
Five-year survival rates: unilateral 84%, bilateral 78%.
-
3
HPV positivity in 92.6% of patients.
-
4
Oropharyngeal hemorrhage: 6% for both procedures.
-
5
No significant difference in swallowing outcomes between groups.
-
6
The study was retrospective, which introduces potential bias.
-
7
Unilateral surgery does not compromise outcomes for HPV-positive patients.
-
8
Decision-making should be patient-specific within a multidisciplinary context.
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